Information for Paper ID 6056
Paper Information:
Paper Title: Dual-Mode Microelectrode Array Featuring 20k Electrodes and High SNR for Extracellular Recording of Neural Networks 
Student Contest: Yes 
Affiliation Type: Academia 
Keywords: Microelectrode array, active-pixel-sensor, switch-matrix, full-frame, signal-to-noise ratio 
Abstract: In recent electrophysiological studies, CMOS-based high-density microelectrode arrays (HD-MEA) have been widely used for studies of both in-vitro and in-vivo neuronal signals and network behavior. Yet, an open issue in MEA design concerns the tradeoff between signal-to-noise ratio (SNR) and number of readout channels. Here we present a new HD-MEA design in 0.18 μm CMOS technology, consisting of 19,584 electrodes at a pitch of 18.0 μm. By combing two readout structures,namely active-pixel-sensor (APS) and switch-matrix (SM) on a single chip, the dual-mode HD-MEA is capable of recording simultaneously from the entire array and achieving high signal-to-noise-ratio recordings on a subset of electrodes. The APS readout circuits feature a noise level of 10.9 μVrms for the action potential band (300 Hz - 5 kHz), while the noise level for the switch-matrix readout is 3.1 μVrms. 
Track ID:
Track Name: Electronics for Neuroscience 
Final Decision: Accept as Lecture 
Session Name: Lab-on-Chip, Point-of-Care Technologies & CAS for Neuroscience (Lecture)